Duration:
2-12 months

PUBLICATIONS: https://www.researchgate.net/profile/Mayukh-Bose/research
 
DEVELOPMENT OF DRUG-NANO CONJUGATE FOR THERAPEUTICS (PATENT PENDING)
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PLANT PROBIOTICS AND ANTI-INFLAMMATORY EFFICACY (PATENT PENDING)
 
DEVELOPMENT OF METABOLITE CONJUGATE FOR TREATMENT OF ARGULUS INFECTION IN CARP FISH (PATENT PENDING)

DEVELOPMENT OF HYDROPHILIC METABOLITES AS PLANT PESTICIDES (PATENT PENDING)

TO EXTRACT, ISOLATE, PURIFY & CHECK THE EFFICACY OF PURE METABOLITES CONJUGATED NANOPARTICLES (TRIMYRISTIN, HYDROXYCHAVICOL, GLYCYRRHIZIN, COUMARIN, ANTHOCYANIN, LIMONENE, ARECOLINE-ARECAIDINE, VINBLASTINE, STEVIOSIDE, ALLICIN, IRIDOIDS, NIMBIN) & TO EVALUATE THEIR EFFICACY IN SYSTEMS BIOLOGY, ANTI-THYROID, ANTI-DIABETIC, ANTI-COAGULANT, ANTI-CANCER, APOPTOSIS, ANTI BCL-2 EXPRESSION AND REACTIVE OXYGEN SPECIES ACTIVITIES IN STEM CELL, MDA MB-231, MCF-7, AND HELA CELL LINES K60​
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BIODEGRADATION OF PLASTICS USING MICROORGANISMS: ANALYSIS OF PETASE ENZYME ACTIVITY, PROTEIN COMPARISON, FTIR SPECTROSCOPY, AND GENETIC MODIFICATIONS K30
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EVALUATION OF BLATEM GENE EXPRESSION IN GENETICALLY MODIFIED BACTERIA FOLLOWING MINIMUM INHIBITORY CONCENTRATION ANALYSIS OF WILD-TYPE AND GENETICALLY MODIFIED BACTERIA WITH CHITOSAN NANOPARTICLE-DRUG CONJUGATES, INCLUDING PHYLOGENETIC TREE ANALYSIS, DISTANCE MATRIX, MULTIPLE SEQUENCE ALIGNMENT, AND SEQUENCE SIMILARITY K30
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EXTRACTION, ISOLATION, AND PURIFICATION OF PURE METABOLITES AND THEIR CONJUGATION WITH POLYMER NANOPARTICLES TO ASSESS THE EFFICACY AGAINST POLYMICROBIAL SEPSIS IN MAMMALIAN SERUM (HOST-PATHOGEN INTERACTION) AND ANTI-CANCER ACTIVITY IN MDA MB-231 CELL LINES K30

TO ISOLATE & CHECK THE EFFICACY OF PURE METABOLITES CONJUGATED NANOPARTICLES IN SYSTEMS BIOLOGY, POLYMICROBIAL SEPSIS IN MAMMALIAN SERUM (HOST-PATHOGEN INTERACTION), ANTI-FUNGAL, ANTIOXIDANT & ANTI-COAGULANT ACTIVITY K30
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INTEGRATED OMICS-DRIVEN PIPELINE FOR NANOCOATED METABOLITE DISCOVERY AND GENOMIC VALIDATION IN DRUG DEVELOPMENT COVERING METABOLOMICS, GENOMICS & PROTEOMICS (a multidisciplinary approach to drug development, beginning with the selection of a plant, fungus, or bacterium for metabolite sourcing. Metabolites are finalised using databases like IMPAAT, KNApSAcK, PubChem, and MassBank within metabolomics, followed by drug likeness assessment via MolSoft. The drug is remodelled with nanocoating, and its nanoconjugate is docked, with toxicity evaluated using ProTox and details sourced from Swiss, STITCH, and SuperPred. Gene targets are identified using GeneCard and OMIM, with gene comparisons and common genes analysed using Venny. KEGG pathways are explored through ShinyGO. Gromacs simulations enhance structural insights, and genomics/proteomics analyses involve Fasta and BLAST of the modulating gene/protein. Further genomics steps include sequence similarity, multiple sequence alignment, diversity, ancestry, phylogenetic and BLAST tree construction, mutation diagnosis with primer design, and NGS data analysis of the source organism) K30

DEVELOPMENT OF NOOTROPIC FORMULATIONS WITH SUSTAINED RELEASE USING POLYMER NANOPARTICLES K15
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EXTRACTION, ISOLATION, AND PURIFICATION OF LIMONENE AND ITS CONJUGATION WITH POLYMER NANOPARTICLES TO EVALUATE EFFICACY AGAINST POLYMICROBIAL SEPSIS INFECTIONS K15
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COMPARATIVE ANALYSIS OF SHELF LIFE BETWEEN COMMERCIAL BAKED GOODS AND HOMEMADE ITEMS, HIGHLIGHTING THE ROLE OF ADDITIVES AND EMULSIFIERS IN COMMERCIAL PRODUCTS AND THEIR IMPACT ON GUT MICROBIOTA K15
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EXTRACTION, ISOLATION, AND PURIFICATION OF A SECONDARY METABOLITE AND ASSESSMENT OF ITS ANTIMICROBIAL ACTIVITY AGAINST BIOFILMS AND POLLUTED WATER BODIES CONTAMINATED BY DIVERSE BACTERIAL LOADS K15
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PRODUCTION OF BIOFERTILIZERS AND COMPARATIVE EVALUATION WITH SYNTHETIC FERTILIZERS ON THE ROLE OF PHYTOHORMONES IN PLANT GROWTH THROUGH IN-VITRO AND IN-VIVO TESTING K15
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COMPARATIVE STUDY OF SHELF LIFE BETWEEN COMMERCIAL AND HOMEMADE CANDIES, EMPHASIZING THE USE OF FOOD COLORING AGENTS IN COMMERCIAL PRODUCTS AND THEIR EFFECTS ON GUT MICROBIOTA K15
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DEVELOPMENT OF GENETICALLY MODIFIED PROBIOTIC-PREBIOTIC CONJUGATES WITH POLYMER NANOPARTICLES AND EVALUATION OF THEIR EFFICACY AGAINST GUT-BASED PATHOGENS K15
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PROTEIN EXPRESSION, ISOLATION, AND PURIFICATION FROM GENETICALLY MODIFIED MICROBES AND ASSESSMENT OF THEIR EFFICACY AGAINST PATHOGENIC CULTURES K15
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INVESTIGATION OF ANTIMICROBIAL RESISTANCE OF ARTIFICIAL PRESERVATIVES AND ADULTERANTS IN MILK K15
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UTILIZATION OF BACTERIAL PROTEINS AND BACTERIOCINS WITH NANOPARTICLE CONJUGATES IN THE INHIBITION OF BIOFILM-RELATED INFECTIONS K15
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PREPARATION OF ORGANIC BIOPESTICIDES AND MICROBIAL BIOFERTILIZERS WITH IN-VITRO AND IN-VIVO TESTING K15

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ANTIMICROBIAL EFFICACY OF SILVER, COPPER, OR ZINC NANOPARTICLES AGAINST POLYMICROBIAL INFECTIONS K15

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ISOLATION OF BIOACTIVE COMPOUNDS FROM PLANTS AND EVALUATION OF THEIR ANTIBIOFILM PROPERTIES K10
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DEVELOPMENT OF AN EFFECTIVE ORGANIC ORANGE-BASED HAND SANITIZER AGAINST ENVIRONMENTAL PATHOGENS K10
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ISOLATION AND CHARACTERIZATION OF CELLULASE FROM BACILLUS SUBTILIS K10

MICROBIAL CLASSIFICATION & CHARACTERIZATION OF DIFFERENT SOURCES OF WATER AND ITS PHYLOGENETIC TREE ANALYSIS K10

CHARACTERIZATION OF PATHOGENS FROM DIFFERENT SOIL SOURCES AND THEIR PHYLOGENETIC ANALYSIS K10
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EVALUATION OF THE BENEFICIAL EFFECTS OF PROBIOTICS AND PREBIOTICS AGAINST PATHOGENIC ENTEROBACTERIACEAE K10